Principal Investigators

Linda L. Demer, MD, PhD

Office: (310) 206-2677

Linda Demer is a Professor in the Departments of Medicine (Cardiology), Physiology and Bioengineering. She received her MD and PhD in biomedical engineering from Johns Hopkins.  She has over 35 years of research experience and NIH funding, with a focus on vascular biology and regulatory mechanisms of cardiovascular calcification. Her research interests also include related fields of reaction-diffusion pattern formation, cellular self-organization, biomechanics, right-left chirality in migration, mathematical modeling, positron imaging, , circulatory physiology, inflammatory cytokines, exercise, and skeletal biology. Her editorial service includes membership the Editorial Boards for Circulation, Vascular Pharmacology, Circulation Research, and Arteriosclerosis, Thrombosis and Vascular Biology and serving as Associate Editor for the latter two journals.  She also served as a charter member and chair of NIH study sections, co-chaired the Gordon Research Conference on atherosclerosis and served as President of the Association of Professors of Cardiology, the Western Society for Clinical Investigation, the Association of University Cardiologists, and the North American Vascular Biology Organization.


Yin Tintut, PhD

Office: (310) 206-9964

Dr Tintut received her Ph.D. in the Department of Biochemistry at University of California, Los Angeles in 1995. She has since joined David Geffen School of Medicine as a faculty. She has secondary appointments in the Department of Physiology and Orthopaedic Surgery, serving as an organizer of Musculoskeletal Seminar Series, a Director of Physiology Teaching Laboratory, and a Safety Committee Chair for the Department of Physiology. She also serves as an Academic Editor at PLOS One and an Associate Editor for Atherosclerosis and Vascular Medicine at Frontiers in Cardiovascular Medicine.  



Jeffrey Hsu, MD, PhD

Office: (310) 794-7105

Dr. Hsu is an Assistant Clinical Professor of Medicine at the David Geffen School of Medicine at UCLA, and he is also an Affiliate Faculty Member of the UCLA Department of Bioengineering. He received his undergraduate education at MIT, where he earned degrees in Mechanical Engineering and Biology, and he subsequently received a Masters of Engineering in Biomedical Engineering at MIT. He attended medical school at the David Geffen School of Medicine at UCLA, and completed his Internal Medicine residency training at UCSF Medical Center. He completed his General Cardiology and Advanced Heart Failure/Transplant fellowships at UCLA. He received his Ph.D. in the UCLA Molecular Cellular & Integrative Physiology department. His editorial service includes serving as a Technical Editor for Circulation and an Editorial Board member of ATVB.  In his free time, he enjoys running, biking, rooting for the Dodgers and Lakers, and spending time with his family and friends. 

Lab Members 

Qian Li, MD, PhD

I am currently a Post-Doctoral Fellow in Professor Hsu’s lab. I got my M.D. in China and finished my doctoral study in molecular cardiology in Germany. My research interest mainly involved the clinical and basic research of cardiovascular diseases, focusing on molecular insights into vascular pathophysiology. This is primarily achieved through exploring mechanisms in the development of endothelium dysfunction. Besides research, I like cooking, traveling with my family, and running a lot.


Yonghong Meng, MD

I have been an SRA in the Department of Cardiology in UCLA for more than 13 years. before I coming to UCLA, I worked as a research associate in Wayne State University and Medical College of Georgia for more than 10 years.  In my leisure time, I like to travel, cook, listen to music and watch movies.


Mimi Lu

I earned my Bachelor's degree in Physiological Science here at UCLA in 2018. I am excited to continue working in research as well as learning and growing in this lab. 


Andy Hon

I am a 4th year biology major from Orange County, California. My main research interests include exploring heart function by echocardiography, investigating bone density using CT imaging, and analyzing atherosclerotic calcification. One of the most rewarding experiences I’ve had so far was working on experiments involving mice treadmill exercise regimens in our lab. When I’m not busy with my studies and research, I love riding dirtbikes, playing basketball with friends, and camping.


Sophia Kalanski

I am currently a 4th year student majoring in psychobiology. I grew up in Irvine, California. Currently at the Demer-Tintut Laboratory, I study the effects of empagliflozin, an SGLT2 inhibitor, on both spontaneous and TNF-a-induced osteoblastic differentiation and calcification of mouse aortic smooth muscle cells. I have loved my experience thus far exploring and contributing to the research aspects of medicine and want to continue doing research in my future professional career. I am currently on the pre-med track at UCLA and my professional goal is to become a physician. In my free time, I like to go on walks around Westwood, go to the beach, cliff jump, and get boba with friends!


Stuti Pradhan

I am currently a 4th year Human Biology and Society student with a minor in Education Studies. I grew up in NorCal and was involved with Sports Medicine in high school. I also studied the design of substrates of aPKC (a protein commonly dysregulated in cancer) in order to create an effective pseudosubstrate inhibitor. Beginning in my first year of college, I joined the Cardiovascular Calcification Research Lab (CVCRL) and began researching the effects of Empagliflozin, a drug used to treat diabetes, on bone cells. In my free time, I enjoy hiking, dancing, and exploring new cafes in Santa Monica. 



Jonathan Phan

I am a 4th year undergraduate student majoring in Bioengineering (with a Mechanical Engineering technical breadth) and Life Sciences (still undeclared). Before moving to LA for university, I was originally from South Bay Area. In Dr. Hsu's lab, I am working on an AHA Long Covid project where I characterize the mechanistic role that viral fragments of SARS-CoV-2 play on endothelial cell inflammation. As an extension of my role in this project, I am also training to provide clinical research services where I coordinate appointments with patients to enroll them into this study and retrieve samples. Outside of Dr. Hsu’s research, I participate in population health research as part of Stanford’s CARE Scholars program. At UCLA, organizations I partake in include BMES, EMRA, and CityLab. In my spare time, I like to play board games, volleyball, and fuseball with family and friends. Other things I do for fun include making vlogs, hosting presentation nights, and watching Modern Family religiously.


Yuxuan Shirley Xia

I am a 3rd year undergraduate student enrolled in the Computational and Systems Biology program at UCLA, with a minor in Data Science Engineering. My primary academic focus revolves around the application of computational methodologies to address biological challenges. Currently, I am actively engaged in research related to image processing, data extraction, and statistical analysis of CT scans. Outside of my academic pursuits, I enjoy dedicating my free time to the company of exotic pets, engaging in the art of taxidermy, and pursuing my passion for painting.


Rahi Patel

I am currently a 2nd year pre-med undergraduate student majoring in Human Biology and Society. I was born and raised in Anaheim, California. My professional goal is to become an orthopedic surgeon with a specialization in sports medicine. In my free time, I love to watch and root for Steph Curry, play basketball and tennis with my friends, listen to rap and hip-hop music, hang out with friends and grab food, and love to travel whenever I have the time to with family and friends. 





Atherosclerosis Research Laboratory

Tara Aghaloo, Flavia Pirih, Sotirios Tetradis

Maria-Grazia Ascenzi

Cecil Chen

Rita Effros

Daniel Ennis

Michael Fishbein

Alan Fogelman

Alan Garfinkel

Lucia Graham (Effros Lab)

Chih-Ming Ho

Henry Honda

Tzung Hsiai

Louis Ignarro

William Klug

Mohammad Navab

Renata Pereira

Jian-Hua Qiau

Tamer Sallam

Yisidro Salusky

Theodore Sarafian

Stephanie Seidlits

Jonathan Tobis

Natalie Van Venrooij (Salusky/Wesseling-Perry/Pirih Lab)

Katherine Wesseling-Perry


Other Institutions

Gail Bishop, University of Iowa

Yabing Chen, University of Alabama

Iris Jaffe, Tufts University

Ivo Kalajzic, University of Connecticut

Gerard Karsenty, Anderson Medical Center

Michael Mendelsohn, Tufts University

Makoto Miyazaki, University of Colorado-Denver

David Rowe, University of Connecticut

Dwight Towler, UT Southwestern


Post Graduate

Sriharsha Talapaneni 

Moeen Abedin

Kristina Bostrom

Henry Cheng

Daniel DeUgarte

Xin Li

Jina Lim

Nilam Mody

Sean Morony

Farhad Parhami

Kris Radcliff

Andrew Sage

William Standford

Karol Watson



Christine Tat

Victoria Le

Alexander Wu

Tri Bang Tang

Vahe Boghossian

John Choe

Jamie Garcia

Yi-Fan Geng

Nima Gharavi

Hung Hyunh

Sidney Iriana

Yevgeniy Ivanov

Christine Kang

 Jennifer Lu

Carolyn Meyers

Ezinna Nnabue

Nikhil Patel

Taylor Pedego, B.S.

Aneela Reddy

Babak Saedi

Trishal Saini

Kulveer Setya

Wendy Tseng

Zina Zhang




Summer Interns

Leilani Dimond, University of Southern California

Trevor Graifman, California Baptist University

Hannah MacDonald, California Baptist University


Laboratory Staff

Jinxiu Lu

Brianne Bear

Andrea Choe

Jason Chu

Larry Hon

Michael Huang

Daniel Park

Steve Tovar

Fei Ye